Skin Renewing Peptide Cream

CeraVe Skin Renewing Peptide Night Cream is a moisturising night cream formulated to help renew and soften the look of tired skin while you sleep. Developed with dermatologists and suitable for all skin types, it is powered by a biomimetic peptide complex — including tripeptide-1 and caprooyl tetrapeptide-3 — which helps to enhance the appearance of tired-looking skin, promote plumpness, and counteract the visible signs of ageing associated with sleep deprivation. MVE (MultiVesicular Emulsion) Delivery Technology continuously releases moisturising ingredients throughout the night for sustained overnight hydration. The formula helps restore and maintain the skin's moisture barrier, resulting in visibly firmer, calmer, plumper-looking skin.

CeraVe Skin Renewing Peptide Night Cream is suitable for all skin types and is particularly well suited to those who want to address the visible signs of ageing — such as fine lines, dullness, and loss of firmness — as part of their evening skincare routine. It is especially beneficial for those whose skin looks tired or dull, as the biomimetic peptide complex is specifically formulated to enhance the appearance of tired-looking skin overnight. Its fragrance-free, non-comedogenic formula also makes it appropriate for those with sensitive skin. Because it is an evening product designed to work overnight, it is recommended to use it as the final moisturising step in a dedicated night skincare routine.

The hero ingredients are two biomimetic peptides — tripeptide-1 and caprooyl tetrapeptide-3 — which work together to enhance the appearance of tired-looking skin and help promote plumpness and volume for firmer-looking skin. Three essential ceramides (ceramide NP, ceramide AP, and ceramide EOP) help restore and maintain the skin's protective moisture barrier, replenishing ceramides naturally lost through ageing. Hyaluronic acid (as sodium hyaluronate) and saccharide isomerate attract and retain moisture in the skin. Niacinamide (vitamin B3) helps calm the skin and supports a more even skin tone. Shea butter provides additional nourishment. Allantoin soothes the skin. MVE Delivery Technology ensures continuous overnight release of moisturising ingredients. The formula is free from fragrance.

• Time of Day: Apply CeraVe Skin Renewing Peptide Night Cream to a freshly cleansed face every evening before bed.
• Amount: Dispense small dots of the cream around the face and gently massage in until thoroughly absorbed. Avoid the eye area.
• Pair with: For best results, CeraVe recommends preceding the application with CeraVe Moisturising Cream or layering it as the final step in your evening routine after any serums or treatments. Because this is a night cream designed to work while you sleep, it should not be used in place of a daytime moisturiser with SPF — always apply a broad-spectrum SPF 50+ sunscreen in the morning to protect the skin from Australia's high UV levels.

Peptides are short chains of amino acids — the building blocks of proteins such as collagen and elastin that give skin its structure, firmness, and elasticity. As the skin ages, collagen and elastin production naturally slows, which contributes to the appearance of fine lines, loss of firmness, and skin that looks tired or dull. Biomimetic peptides — like those used in CeraVe Skin Renewing Peptide Night Cream — are designed to mimic the skin's own peptides, helping to signal processes that support the skin's appearance. The specific peptide complex in this formula (tripeptide-1 and caprooyl tetrapeptide-3) is formulated to enhance the appearance of tired-looking skin, improve visible plumpness, and counteract the visible effects of insufficient sleep on the skin.

Yes. CeraVe Skin Renewing Peptide Night Cream is generally well tolerated alongside other anti-ageing actives and can be layered as the final moisturising step in an evening routine that includes serums such as CeraVe Renewing Retinol Serum or CeraVe Skin Renewing Vitamin C Serum (used in the morning). Peptides are generally considered compatible with most skincare ingredients and are not known to cause the irritation associated with stronger actives like retinol or exfoliating acids. If using multiple actives in one routine, apply in order of thinnest to thickest texture — serums before creams — and allow each to absorb before applying the next. Those with sensitive skin should introduce new products gradually.

Yes. CeraVe Skin Renewing Peptide Night Cream is formulated to be suitable for all skin types, including sensitive skin. It is fragrance-free and non-comedogenic, and the biomimetic peptide complex it contains is a gentle, well-tolerated anti-ageing ingredient that does not cause the sensitivity or irritation that stronger actives like retinol or high-concentration AHAs can. The inclusion of allantoin and niacinamide further supports skin comfort and soothing. As with any new skincare product, those with a diagnosed skin condition or known skin sensitivities are advised to patch test before full-face application and consult a dermatologist if needed.

Both are evening moisturisers designed for overnight use, but they differ in texture, formulation focus, and specific benefits. CeraVe PM Facial Moisturising Lotion is a lightweight, fluid lotion ideal for daily night-time use across a broad range of skin types — its focus is on gentle hydration, barrier support with ceramides, and mild brightening via niacinamide. CeraVe Skin Renewing Peptide Night Cream is a richer, cream-based formula with a specific anti-ageing focus — it contains a dedicated biomimetic peptide complex designed to target the visible signs of ageing and tired-looking skin overnight, as well as shea butter for additional nourishment. The Peptide Night Cream is the better choice for those with concerns about skin ageing, loss of firmness, or visible dullness, while the PM Lotion suits those seeking lightweight daily hydration.